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Botulinum Toxin - 5 Vials x 150 IU

Botulinum Toxin - 5 Vials x 150 IUPackage: 5 Vials x 150 IU

Usage: Injectable

Botox (Botulinum toxin type A) is used cosmetically to improve facial wrinkles,also to treat strabismus,spasm of the eyelids,blepharospasm,severe underarm sweating,etc.

Produced by: China


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Botulinum Toxin type A 150 IU, Buy Botulinum Toxin type A 150 IU Online


Brand name: Botulinum Toxin 150 IU, BTXA;
Generic name: Botulinum Toxin;
Active ingredient: botulinum toxin type A;
Inactive ingredients: human albumin and sodium chloride;
Manufacturer: China;
BTXA (Botulinum Toxin Type A for Therapy)

DESCRIPTION:
Botulinum Toxin Type A is category-A toxin that has 150 IU in one vial and can be indicated into one patient. Botulinum Toxin Type A is a kind of medication to correct small folds as well as shrink the face.
This product is a sterilized, lyophilized form of cleaned botulinum toxin type A, formed from the basic toxin of the culture of the Hall strain of Clostridium botulinum grown in a medium enclosing trypticase also yeast extract. A series of cleansing formula were used to form a galssy complex containing of the active high molecular weight toxin protein also an connected hemagglutinin. After re-dissolved and dialyzed the transparent toxin, a correct amount of the germ-free clarified (0.2 microns) toxin were added to a solution containing gelatin-dextran-sucrose, and then lyophilized. Each vial of BTXA contains 100 or 50 units (U) of C. botulinum toxin type A, 5 mg of gelatin, 25 mg of dextran and 25 mg of sucrose.

INDICATIONS:
This injection is administrated for the cure of blepharospasm, hemi facial tremor in adults and some categories of strabismus, particularly for severe paralytic strabismus, comitant strabismus, strabismus instigated by endocrine myopathy and strabismus which cannot be adjusted through surgery. Anti-Wrinkle, Thin looks and legs.

USAGE AND DOSAGE:
1. Position for inoculation:
- For blepharospasm: the inoculation should be used intramuscularly at several places of superior also inferior lids, i.e., using 4 to 5 points of injection into orbicularis oculi of medial and lateral or lateral canthus temporal.
- For hemi facial tremor: besides the locations mentioned above, three other points on middle, lower face also cheek have to be inserted intramuscularly. BTXA can be used at the points of two sides of eyebrow, upper lip or the lower jaw agreeing to the diseases.
- For strabismus: the BTXA is inserted using a coaxial electrode needle with electromyography regulation or amplifier under topical anesthesia of 0.5% Decarine. The insertions into extra ocular muscles are selected agreeing to the form as well lacation of strabismus.

2. Measure:
150 IU should be dissolved into 2.0-2.5ml sterilized water before administrating.
Thin with sterile normal saline agreeing to different requests before injecting. The white loose product changes to be neutral or yellowish clear solution after the reconstitution.
- For blepharopasm also hemi facial tremor: the injection can be indicated following above advices. The primary measure of each point is 2.5 U/ 0.05ml or 2.5 U / 0.1 ml. In case the primary dealing is considered inadequate 1 week later, an extra inoculation could be indicated. Double dosage of 5 U / 0.1 ml can be indicated to recrudescent persons. But the limitation of complete dosing of 55 U for one insertion and 200 U for 1 month must not be overdone.
- For strabismus: for vertical and horizontal muscle strabismus of less than 20 prism diopters, the primary measure into every muscle is 1.25-2.5 U; for horizontal strabismus of 20-40 prism diopters, the primary measure into each muscle is 2.5 U; for horizontal strabismus of 40-50 prism diopters, the initial measure into each muscle is 2.5 U also could be increase (to 5.0 every) depending on the reaction; for persistent VI cranial nerve paralysis continued for more than 1 month. The inserting volume into each muscle should not exceed 0.1 ml. To people, having insufficient response, additional inoculation can be given. To recrudescent persons, the dosing could be repeated or increased irregularly. But for each muscle the supreme dose must be less than 5 U / inj.

The Watering of BTXA (Botulinum Toxin Type A for Therapy):
The dissolving of BTXA (Botulinum Toxin Type A for Therapy) with sterile normal saline must be done carefully on the basis of real desires. Following is a reference table of thinning to be mentioned. The vial must be shaking lightly once adding sterile normal saline to the complete watering. The dissolving BTXA (Botulinum Toxin Type A for Therapy) should be administrated at once or maintained in freezer at 2 to 8 degrees and to be administrated within 4 hours. The dish as well as the syringe used with this product also the remaining BTXA solution should be disposed after disinfection.

UNDESIRABLE REPLIES:
Short-term ptosis of the eyelid, disadvantage of the minor eyelid, minimized blinking, eyelid close in part, weakness of facial muscles, etc. can happen to a few people who take this medication remedy for blepharospasm as well hemi facial tremor. However, all the indications will vanish without any treatment within three to 8 weeks. Momentary also dissimilar degree of ptosis of the eyelid, vertical deviance also seldom mydriasis, which connected to the circulation of the toxin to the muscles nearby, may appear to some individuals who take this preparation therapy for strabismus. The symptoms will disappear without any therapy within a few weeks.

CONTRAINDICATIONS:
BTXA is not recommended in people with anaphylactic structure and known reaction to this medication.

WARNINGS:
The insertion procedure has to be indicated later to patients who have infection, grave infectious diseases also prudently to the persons with heart, liver, lung malady, active tuberculosis, blood diseases also pregnant women.
Botulinum toxin can be potentiated by aminoglycoside antibiotics (such as gentamicin).This kind of products should not be taken during the administration of BTXA (Botulinum Toxin Type A for Therapy).
BTXA is in low effect or without any effect to the patients in the following situations: strabismus above 50 prism diopters, fixed strabismus, strabismus initiated by excessively corrected operation, chronic paralysis strabismus, and chronic VI or III cranial nerve paralysis, severe muscle fiber contracture.
1:1000 adrenalines should be set in case of occasional accident.

EXPIRATION:
3 years from the day of lyophilization. The effect is obvious and can be last six months.

STORAGE:
Store at a temperature of -5 to -20 gr C (23 to -4 gr F). Store new vial at -5 temperatures.

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