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Botulinum Toxin - 10 Vials x 150 IU

Botulinum Toxin - 10 Vials x 150 IUPackage: 5 Vials x 150 IU

Usage: Injectable

Botox (Botulinum toxin type A) is used cosmetically to improve facial wrinkles,also to treat strabismus,spasm of the eyelids,blepharospasm,severe underarm sweating, etc.

Produced by: China


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Botulinum Toxin type A 150 IU, Buy Botulinum Toxin type A 150 IU Online


Brand name: Botulinum Toxin 150 IU, BTXA;
Generic name: Botulinum Toxin;
Active ingredient: botulinum toxin type A;
Inactive ingredients: human albumin and sodium chloride;
Manufacturer: China;
BTXA (Botulinum Toxin Type A for Therapy)

DESCRIPTION:
Botulinum Toxin Type A is category-A toxin which contains 150 IU in one vial and may be injected into one patient. Botulinum Toxin Type A is a kind of product to correct small lines and shrink the expression.
This injection is a sterilized, lyophilized formula of cleaned botulinum toxin type A, created from the unfinished toxin of the culture of the Hall strain of Clostridium botulinum grown in a medium having trypticase and yeast extract. A series of purifying process were used to make a crystal clear complex consisting of the active high molecular weight toxin protein as well as an allied hemagglutinin. Next re-diluted and dialyzed the crystal-like toxin, a precise quantity of the hygienic clarified (0.2 microns) toxin were added to a solution holding gelatin-dextran-sucrose, and then lyophilized. Each vial of BTXA has 100 or 50 units (U) of C. botulinum toxin type A, 5 mg of gelatin, 25 mg of dextran and 25 mg of sucrose.

INDICATIONS:
This preparation is indicated for the cure of blepharospasm, hemi facial tremor in adults also some categories of strabismus, especially for serious paralytic strabismus, comitant strabismus, strabismus produced by endocrine myopathy and strabismus which cannot be modified by operation. Anti-Wrinkle, Thin expressions and legs.

USAGE AND MEASURING:
1. Location for inoculation:
- For blepharospasm: the injection must be injected intramuscularly at number of points of upper also lower lids, i.e., taking 4 to 5 places of inoculation into orbicularis oculi of medial and lateral or lateral canthus temporal.
- For hemi facial spasm: besides the points mentioned above, three other points on middle, lower face also cheek should be given intramuscularly. BTXA (Botulinum Toxin Type A for Therapy) can be inoculated at the locations of two sides of eyebrow, upper lip or the lower jaw according to the diseases.
- For strabismus: the BTXA is injected using a coaxial electrode syringe with electromyography regulation or amplifier under topical anesthesia of 0.5% Decarine. The injections into extra ocular muscles are selected according to the variety as well place of strabismus.

2. Dose:
150 IU must be dissolved into 2.0-2.5ml sterilized water before usage.
Melt with sterile normal saline according to different requests before using. The white loose product turns to be neutral or yellowish transparent solution after the thinning.
- For blepharopasm also hemi facial tremor: the injection can be suggested following above directions. The primary dosage of each point is 2.5 U/ 0.05ml or 2.5 U / 0.1 ml. If the first handling is considered insufficient one week later, a supplementary injection may be indicated. Double dosing of 5 U / 0.1 ml could be given to recrudescent individuals. But the limitation of complete dose of 55 U for one insertion and 200 U for 1 month should not be overdone.
- For strabismus: for vertical and horizontal muscle strabismus of less than 20 prism diopters, the primary measure into every muscle is 1.25-2.5 U; for horizontal strabismus of 20-40 prism diopters, the primary dosage into every muscle is 2.5 U; for horizontal strabismus of 40-50 prism diopters, the initial measure into every muscle is 2.5 U also could be increase (to 5.0 every) depending on the reaction; for persistent VI cranial nerve paralysis continued for more than one month. The injecting volume into ever muscle must not exceed 0.1 ml. To people, having insufficient reply, additional inoculation could be indicated. To recrudescent persons, the measure can be repeated or improved irregularly. But for every muscle the supreme dosing has to be less than 5 U / inj.

The Thinning of BTXA (Botulinum Toxin Type A for Therapy):
The dilution of this medication with sterile normal saline has to be done sensibly on the basis of real necessities. Following is a reference table of dilution to be suggested. The vial has to be trembling smoothly once adding sterile normal saline to the complete dissolving. The dissolving BTXA must be injected at once or maintained in refrigerator at 2-8 degrees and to be used within 4 hours. The dish also the needle used with BTXA (Botulinum Toxin Type A for Therapy) as well as the lasting BTXA solution has to be disposed after cleansing.

SIDE EFFECTS:
Temporary ptosis of the eyelid, weakness of the minor eyelid, reduced blinking, eyelid close partly, weakness of face muscles, etc. can happen to a few persons who inject BTXA therapy for blepharospasm also hemi facial contraction. However, all the indications will disappear without any cure within three to 8 weeks. Momentary also dissimilar point of ptosis of the eyelid, vertical deviation as well infrequently mydriasis, which associated to the distribution of the toxin to the muscles adjacent, may arise to some patients who received this injection treatment for strabismus. The indications will go without any treatment within a few weeks.

CONTRAINDICATIONS:
This medication is not recommended in people with anaphylactic parts and identified allergy to this medication.

WARNINGS:
The injection procedure must be indicated later to patients who have infection, acute infectious diseases also prudently to the patients with heart, liver, lung diseases, active tuberculosis, blood problems also pregnant women.
Botulinum toxin could be potentiated by aminoglycoside antibiotics (such as gentamicin).This kind of products should not be taken during the using of BTXA.
BTXA is in low effect or without any effect to the persons in the following situations: strabismus above 50 prism diopters, fixed strabismus, strabismus provoked by extremely modified surgery, chronic paralysis strabismus, and chronic VI or III cranial nerve paralysis, serious muscle fiber contracture.
1:1000 adrenalines have to be prepared in case of occasional accident.

SHELF LIFE:
3 years from the date of lyophilization. The effect is clear and can be last 6 months.

STORE:
Store at a temperature of -5 to -20 gr C (23 to -4 gr F). Keep unused vial at -5 temperatures.

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