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Botulinum Toxin - 1 Vial x 150 IU

Botulinum Toxin - 1 Vial x 150 IUPackage: 1 Vial x 150 IU

Usage: Injectable

Botox (Botulinum toxin type A) is used cosmetically to improve facial wrinkles,also to treat strabismus,spasm of the eyelids,blepharospasm,severe underarm sweating,etc.

Produced by: China


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Botulinum Toxin type A 150 IU, Buy Botulinum Toxin type A 150 IU Online


Brand name: Botulinum Toxin 150 IU, BTXA;
Generic name: Botulinum Toxin;
Active ingredient: botulinum toxin type A;
Inactive ingredients: human albumin and sodium chloride;
Manufacturer: China;
BTXA (Botulinum Toxin Type A for Therapy)

DESCRIPTION:
Botulinum Toxin Type A is kind-A toxin which has 150 IU in one vial and may be injected into one patient. Botulinum Toxin Type A is a type of product to correct small wrinkles as well as shrink the look.
This medication is a sterile, lyophilized form of refined botulinum toxin type A, made from the crude toxin of the culture of the Hall strain of Clostridium botulinum developed in a medium containing trypticase as well yeast extract. A series of refining process were used to make a limpid complex containing of the active high molecular weight toxin protein also an connected hemagglutinin. Next re-dissolved and dialyzed the crystal-like toxin, a precise amount of the hygienic cleaned (0.2 microns) toxin were added to a solution holding gelatin-dextran-sucrose, and then lyophilized. Every vial of BTXA contains 100 or 50 units (U) of C. botulinum toxin type A, 5 mg of gelatin, 25 mg of dextran and 25 mg of sucrose.

SUGGESTIONS:
BTXA (Botulinum Toxin Type A for Therapy) is gived for the therapy of blepharospasm, hemi facial spasm in grown-ups also some forms of strabismus, especially for grave paralytic strabismus, comitant strabismus, strabismus instigated by endocrine myopathy also strabismus which cannot be amended with operation. Anti-Wrinkle, Thin faces also legs.

USAGE AND MEASURING:
1. Location for injection:
- For blepharospasm: the inoculation has to be taken intramuscularly at number of places of upper also lower tops, i.e., using 4 to 5 points of injection into orbicularis oculi of medial and lateral or lateral canthus temporal.
- For hemi facial spasm: besides the points mentioned above, three other locations on middle, lower face and cheek should be inoculated intramuscularly. BTXA (Botulinum Toxin Type A for Therapy) can be used at the places of two sides of eyebrow, upper lip or the lower jaw agreeing to the illnesses.
- For strabismus: the BTXA (Botulinum Toxin Type A for Therapy) is injected using a coaxial electrode needle with electromyography regulation or amplifier under topical anesthesia of 0.5% Decarine. The injections into extra ocular muscles are selected according to the kind also place of strabismus.

2. Dosing:
150 IU should be dissolving into 2.0-2.5ml sterilized water before usage.
Melt with sterile normal saline according to diverse necessities before administrating. The white loose product turns to be neutral or yellowish translucent solution after the diluted.
- For blepharopasm and hemi facial spasm: the inoculation could be suggested following above guidelines. The primary measure of each point is 2.5 U/ 0.05ml or 2.5 U / 0.1 ml. If the primary dealing is considered deficient one week later, an additional inoculation could be suggested. Dual measure of 5 U / 0.1 ml may be indicated to recrudescent persons. But the limitation of complete dosing of 55 U for one insertion and 200 U for one month must not be exceeded.
- For strabismus: for vertical as well horizontal muscle strabismus of less than 20 prism diopters, the initial dose into every muscle is 1.25-2.5 U; for horizontal strabismus of 20-40 prism diopters, the initial measure into each muscle is 2.5 U; for horizontal strabismus of 40-50 prism diopters, the primary measure into each muscle is 2.5 U as well could be increase (to 5.0 every) depending on the reaction; for persistent VI cranial nerve paralysis continued for more than 1 month. The inoculating volume into ever muscle should not ever 0.1 ml. To individuals, taking insufficient reply, extra insertion could be given. To recrudescent persons, the dosage may be repeated or amplified irregularly. But for every muscle the supreme dose should be less than 5 U / inj.

The Watering of BTXA (Botulinum Toxin Type A for Therapy):
The dilution of this injection with sterile normal saline should be done carefully on the basis of real necessities. Following is a reference table of watering to be recommended. The vial must be shaking mildly once adding sterile normal saline to the whole thinning. The reconstituted BTXA (Botulinum Toxin Type A for Therapy) has to be administrated at once or maintained in ice-box at 2 to 8 degrees and to be administrated within 4 hours. The container and the syringe used with this preparation as well as the lasting BTXA solution must be prepared after purification.

UNWANTED REACTIONS:
Temporary ptosis of the eyelid, disadvantage of the lesser eyelid, reduced blinking, eyelid close in part, softness of face muscles, etc. can happen to a number of persons who received BTXA (Botulinum Toxin Type A for Therapy) cure for blepharospasm also hemi facial spasm. But, all the indications will vanish without any therapy within 3 to 8 weeks. Passing also diverse degree of ptosis of the eyelid, vertical deviance and seldom mydriasis, which related to the distribution of the toxin to the muscles adjacent, may happen to some people who received this medication healing for strabismus. The signs will disappear without any remedy within a few weeks.

CONTRAINDICATIONS:
This preparation is not recommended in persons with anaphylactic parts as well identified allergic reaction to this medicine.

ADVICES:
The insertion technique has to be taken later to people who have temperature, acute infectious malady also prudently to the people with heart, liver, lung illness, active tuberculosis, blood problems also pregnant women.
Botulinum toxin can be potentiated by aminoglycoside antibiotics (such as gentamicin).This kind of medicines must not be taken during the administration of BTXA (Botulinum Toxin Type A for Therapy).
BTXA is in minim reaction or without any effect to the persons in the next situations: strabismus above 50 prism diopters, fixed strabismus, strabismus initiated by extremely modified operation, chronic paralysis strabismus, and chronic VI or III cranial nerve paralysis, serious muscle fiber contracture.
1:1000 adrenalines have to be prepared in case of occasional accident.

SHELF LIFE:
3 years from the date of lyophilization. The effect is clear and can be last 6 months.

STORAGE:
Store at a temperature of -5 to -20 gr C (23 to -4 gr F). Keep unopened vial at -5 temperatures.

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